Fightin' Irish Offense v. Fightin' Falcon Defense: Notre Dame just needs to play efficient, mistake-free football. Exploiting mismatches should be easy, as Air Force literally won't be able to cover bigger receiving threats like Troy Niklas or Davaris Daniels. The Fightin' Falcons rank outside the top 100 in terms of both pass and rush defense, giving up over 37 points on average every game. Look for the Fightin' Irish to top that total by putting up at least 40.
Fightin' Irish Defense v. Fightin' Falcon Offense: Every member of Diaco's defense must stay disciplined and track all of their assignments. Air Force impressively ranks 12th when it comes to yards gained on the ground, so Notre Dame should know what they're in for. It might take a quarter or two to adjust, but by the time the second half rolls around the Fightin' Irish will have worn down their opponents' rushing attack.
Final Outcome: The only way Air Force can possibly win is by playing keep-away. If they can consistently average 3+ yards per carry with their Triple-Option attack, they may be able to limit Notre Dame's possessions enough to keep the game close. If that happens, the final score will reflect the turnover differential. Luckily, I don't think any of that will happen. Notre Dame has far too much talent on both sides of the ball for the Fightin' Falcons to hang. Expect ND to cover the spread.
Fightin' Irish: 41